The second edition of Eclipse Phase gets it right. The simplified resleeving (and therefore actually as common as the setting would have you believe), the skills that make sense, the improved and more accessible character creation...
I have been playing all through the playtest, and the mechanics are well polished and work wonderfully.
As for the rest of the book, the two-page spreads are so intuitive to navigate and just make sense. Notable examples for me include the history of the Fall timeline, gear categories, and combat pages.
The condensed System Gazeteer makes it easier to look up & grok locations on the fly, and make planning sessions easier, a huge improvement on the design of 1E. The setting information, including where we are and transhuman culture, are succinct and make it incredibly easy to on-board new players.
There's so much more good to say about 2E, but i'll leave that for another time.
[5 of 5 Stars!]