This is the weakest book in the Sorcerer's Crusade line, in many ways. Much of it is devoted to general knowledge about the Renaissance. Unfortunately, much of this is factually incorrect, long-debunked claims, for instance, a failure to understand that a Life Expectancy at Birth that's low doesn't mean that most people who grow to adulthood don't make it to 40 (factoring out child and infant mortality, the number for aristocrats in England hits about 70 during this time period, which suggests that even peasants can expect to see their late 40s or 50s if they make it to adulthood). There was also a tendency to treat Europe as a coherent whole, rather than a mess of conflicting norms from different groups. Venice and London in 1500 are wildly different places, as is Seville, and Byzantium in 1452 and 1454 were nearly unrecognizable to one another (the Ottoman conquest was 1453).
I can't comment much on how sensitive portrayals of other outsider groups were, but the Jewish craft, the Lions of Zion, is clearly well-meaning, if entirely awkward in construction. Though I am not a fan, particularly of the name (why would 15th-16th century Jewish mystics in Israel have a name that rhymes in English?) they're presented in a way that is harmless enough, and with a cautioning towards the misuse of Kabbalah.
Overall, there are good things in the book, but on balance it comes off as mediocre, which is damning in a line that is otherwise so good.