This is a decent work. The setting is a man-made island, which is very nicely mapped, something you don't always see. Myself, I would have placed it in a RL city because maps are easy to come by, but no problem.
The product's art is second-rate, but not enough to detract.
It begins with a very good piece of intro fiction.
The blurbs selling the game do a good job of presenting the concept-a mutated virus creates supernatural-like beings which the PCs battle. Its an innovative concept in its presentation.
The downside is that nearly every great idea is countered by a less-than-great counterpart. The setting of a man-made island-city is offset by the idea that the US military would build a biowar facility under this dense urban population, where security was easily compromised, and where a perimeter failure would infect millions. Since the PCs are gov't agents, this means they are employed by, and rely on, idiots.
The game has an extensive weapons list and provides pages of illiustrations of the weapons, a very good idea. However, instead of using clipart or the professional line drawings avalible everywhere (the weapons are modern day) they use freehand drawings done by someone who does not own a ruler.
A terrible idea was the linkage of in-game terminology to religious concepts (DEVIL virus, archangel counter-chips), which is offensive to some religions and comes across as very juvenile. It badly damages the overall tone of what strives to be a grim, dark setting.
In all, not a bad game; the designers break some new ground and present some things in a new light. A fair buy at $10, but its no AFMBE.