This game system is the gold-standard for solo RPGs and GM-ing with improv. I can't recommend it enough.
The rules are low crunch and drive the story forward with twists and turns and complications. The oracle/random tables are delicious and well-organized.
The setting is cool, but far too "perilous". The oracle tables and world-generation procedures create a space sector that I have a hard time suspending my disbelief about. The scarce resources, low populations, limited trade, and hostile environments all make for a world that would quickly extinguish human life.
Luckily, the game system is perfectly capable of driving a campaign in a homebrew Sci Fi world (or a world of fantasy or other genres, for that matter). The oracle tables are still great in a more hospitable and thriving Sci Fi universe, but you will need paint the broad brushstrokes of that universe yourself.
If you can't find a group to play with consistently, if you're a forever-GM who wants to play a character, or if you want a low-crunch system that always drives the story forward, this is the game for you.
Starfoged is a very special contribution to the world of RPGs. I'll be playing it for years to come.