Paranoia's wild and crazy, and not every adventure's gonna be everyone, but it's a lot of fun as a con game or a one shot break between longer campaigns. Doing so avoids the fatigue that comes from attempting to run a serious, long term adventure with it, while maximizing the silly stress relief.

I highly suggest running 'em with the various handout packs that have been created for it over the years. Asking players to fill out customer satisfaction surveys for their deaths never gets old!